Tottenham have won their first trophy for 17 years and they themselves as a candidate for the game at Bilbao, after three times at United this season.
Spurs beat Old Trafford 3-0 at home to beat the Premier League 1-0 at home to 4-3 in the league.
“If you think the club will lose four consecutive times,” he said. “We can think that way.
Former Tottenham midfielder Gleen Hoodle has agreed to win for Spurs.
“You’re four times a season winning a team in the Premier League,” Hodel told TNT Sports.
“It will be a Titanic war. The American Spurs currently had the top hands, but United are looking for revenge,” he said.
The last time United won the Europa League in the 2016-17 season, when Jose Mourinho was coach.
Despite the club’s poor season at home, former Red Devils midfielder Paul Scholes is sure his former club will rise in the final.
“For some reason, the club’s history is close to Real Madrid at times – when they don’t play well as they can continue and win the European Cup,” he said.
“Manchester United’s history tells me they will win, they know how to win the cups, Tottenham will not do it.