Van Der Poel, Gana and Pogakar were winning the first monument this season, but a competition with predicted champions was happy throughout the game.
An eight-member vacation was clear from the beginning before they were captured.
Slovenia’s Pogakar, who is looking for Milan San-Remo’s first title after three consecutive games in five key players, used the UAE-XRG to set a devastating move for Cesc Fabregas before attacking Pojio.
As the riders looked at each other as close to the final consecutive, Van Der Poel took the decisive move, leaving Jenny Inos Grenadis to finish second, as in 2023, Pogakar won third place for the second consecutive year.
They have only six monuments more than Van der Poel and Pogakar, with Gino Bartali, Tom Bonnen and Fabyen Cafelara and seven wins in their career.
Van Der Poel is also the first plural champion of the event since Oscar Freier beat three AC Milan-San titles in 2010 in Spain.
Michael Matthews won the game, finished fourth and ranked fourth in the 10th place.